Vaughn grew up in San Francisco, California. She was married to Derrick Carolina and had a son, Daylen Ali (2001). She is currently married to former football player Karon Riley, and on April 21, 2008 the couple gave birth to a boy, Kal'El Joseph Riley. Vaughn established the non-profit "Take Wings Foundation," which provides scholarships, mentoring and job training opportunities for young women living in public housing in the San Francisco Bay Area.